Collagen Scaffolds in Bone Sialoprotein-Mediated Bone Regeneration

Figure 1

The process of type I collagen synthesis. (a) Two identical α1(I) and one α2(I) peptide chains self-assemble to form procollagen (b). (c) Procollagen peptidase removes loose termini to create a type I tropocollagen molecule (d). Tropocollagen molecules self-assemble to form a growing collagen fibril (e). Self-assembly of collagen fibrils forms a type I collagen fiber (f).