Research Article

Anxiolytic-Like Actions of Fatty Acids Identified in Human Amniotic Fluid

Table 2

Effect of treatment in open field test. The data are expressed as mean ± standard error of the mean. No significant differences in activity time, resting time, or crossings were found between groups.

GroupTime active (s)Time resting (s)Crossings ( )

Vehicle (1 mL)164.8 ± 7.85135.2 ± 7.8598.4 ± 13.69
Artificial fatty acid mixture
 0.125 mL149.6 ± 14.05150.4 ± 14.0592.8 ± 16.01
 0.25 mL133.2 ± 8.34166.8 ± 8.3474.0 ± 10.18
 0.5 mL160.5 ± 13.80139.5 ± 13.8086.8 ± 16.09
 1 mL152.5 ± 14.69147.5 ± 14.6985.0 ± 12.14
Diazepam (2 mg/kg)117.8 ± 18.15182.2 ± 18.1558.2 ± 11.85