Review Article
Bisphophonates in CKD Patients with Low Bone Mineral Density
Table 1
Bone diseases may associate with fragility fractures (low trauma fractures).
| | Name of bone diseases | General metabolic bone diseases | Chronic kidney disease-mineral bone disease (CKD-MBD) |
| | Adynamic bone disease (including aluminum bone disease) | | Yes | | Amyloid bone disease | Yes (AL-amyloidosis.) | Yes (2-microglobulin) | | Mixed uremic osteoporosis | | Yes | | Osteitis fibrosa cystica (severe) | Yes
(primary hyperparathyroidism) | Yes
(secondary hyperparathyroidism) | | Osteogenesis imperfecta | Yes | |
| | Osteomalacia | | | | Vitamin D-related | Yes | Yes | | Nonvitamin D-related | | | | Chronic metabolic acidosis | Yes | Yes | | Phosphate depletion | Yes | Yes |
| | Osteoporosis | | | | Primary osteoporosis | Yes | Yes | | Secondary osteoporosis (all causes) | | | | Chronic liver disease | Yes | | | Hypogonadism or premature menopause | Yes | | | Inflammatory bowel disease | Yes | | | Malabsorption | Yes | | | Steroid-induced osteoporosis | Yes | |
| | Pathologic fractures (malignancies) | Yes | |
| | Paget’s disease | Yes | |
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