Correlation between Ultrasound Reflection Intensity and Tumor Ablation Ratio of Late-Stage Pancreatic Carcinoma in HIFU Therapy: Dynamic Observation on Ultrasound Reflection Intensity
Figure 1
A 64-year-old woman with about 4.9 × 3.5 × 2.9 cm pancreatic body carcinoma. The pre-HIFU isotope scan (a) and PET-CT (b) showed a clear radioactive concentration in pancreas area. The enhanced CT (c) showed low-density lesions in pancreatic body with internal mild heterogeneous enhancement and marginal mild enhancement. Ultrasound showed hypoechoic lesions (d) with clear boundary, internal homogeneous ultrasound reflection, and small blood flow signals (e). In the 6th HIFU treatment, significant increase of ultrasound reflection intensity from tumor central area (f) was observed by ultrasound. Air-like hyperechoic ultrasound reflection (g) without blood flow signals (h) from inside of the tumor was observed by abdominal wall scanning. A month later, CT and enhanced CT showed tumor volume increase with internal uneven low density, no enhancement ((i), (j)), and tumor ablation ratio over 70%.
