Clinical Study

Correlation between Ultrasound Reflection Intensity and Tumor Ablation Ratio of Late-Stage Pancreatic Carcinoma in HIFU Therapy: Dynamic Observation on Ultrasound Reflection Intensity

Figure 3

A 53-year-old man with about  cm pancreatic body carcinoma. The pre-HIFU enhanced CT showed uneven low-density lesions in pancreatic body with mild enhancement in parenchyma in arterial phase (a) and venous phase (b) and liquefaction necrosis. Ultrasound showed hypoechoic lesions ((c) cross section and (d) longitudinal section) with clear boundary, internal heterogeneous echo, and small blood flow signal from around the tumor ((e) cross section and (f) longitudinal section). In the 2nd treatment, ultrasound showed increase of ultrasound reflection intensity within  cm on the right lesions with unclear boundary ((g), (h)). In the 3rd treatment, ultrasound reflection intensity gradually increased with unclear boundary ((i) and (j)). In the 4th treatment, longitudinal ultrasound on the left lesions showed significant increase of ultrasound reflection intensity (k). In the 6th treatment, longitudinal ultrasonography showed increased reflection intensity in the upper area of the lesions (  cm) (l). In the 8th treatment, ultrasound showed significant increase of ultrasound reflection intensity (m). A month later, enhanced CT ((n) arterial phase, (o) venous phase, and (p) coronal-section) showed no internal significant enhancement, but marginal ring enhancement and tumor ablation ratio over 70%. Patient ascites increased due to hypoalbuminemia.
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