Clinical Study

Correlation between Ultrasound Reflection Intensity and Tumor Ablation Ratio of Late-Stage Pancreatic Carcinoma in HIFU Therapy: Dynamic Observation on Ultrasound Reflection Intensity

Figure 4

A 78-year-old woman with about  cm pancreatic body carcinoma. The pre- HIFU enhanced CT ((a) and (b)) and MRI ((c) and (d)) showed inhomogeneous enhancement within the lesions. Ultrasound showed hypoechoic lesions ((e) cross section and (f) longitudinal section) with clear boundary, internal homogeneous echo, and no obvious blood flow signal (g). In the 8th treatment, ultrasound showed increase of ultrasound reflection intensity within  cm ((h) cross section and (i) longitudinal section) on left lesions, but no obvious blood flow signal ((j) cross section and (k) longitudinal section). In the 12th treatment, ultrasound observed significant increase of ultrasound reflection intensity within  cm in the upper area of the lesions ((l) and (m)). In the 19th treatment, ultrasound showed mild enhancement in tumor central area with unclear boundary (n); CDFI showed no obvious internal blood flow signal (o). In the 20th treatment, ultrasound showed internal heterogeneous enhancement with unclear boundary and no blood flow signal ((p) cross section and (q) longitudinal section). After the whole HIFU treatments, ultrasound showed no contrast agent filling within the lesions ((r) 21′′ and (s) 55′′). A month later, enhanced MRI showed no obvious enhancement with the tumor central area (t).
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