NHCs Catalyzed Hydrophosphonylation of 𝜶-Ketoesters and 𝜶-Trifluoromethyl Ketones

Table 2

NHC-catalyzed hydrophosphonylation of phosphites with active ketones^a.

Entry	Ketones	Time (h)	Products	Yield (%)^b
1		24		99
2		24		89
3		24		84
4		24		96
5		24		85
6		24		93
7		24		90
8		48		57
9		24		64
10		48		63
11^c		48		—

aReaction conditions: 7 (1.5 equiv), 6 (1.0 equiv), IPr (10 mol%), and 0.15 mol L⁻¹ of 6.
^bIsolated yield.
^cRecovered yield of acetophenone: 95%.