Application of Response Surface Methodology for Optimizing Arginine Deiminase Production Medium for Enterococcus faecium sp. GR7

Table 5

Regression analysis (ANOVA) for the growth.

Source	Sum of squares	Degree of freedom	Mean squares	F value	P value	Prob > F
Model	8.150	9	0.960	11.228	0.0004	Significant
A-tryptone	3.591	1	3.591	44.527	<0.0001
B-lactose	1.564	1	1.564	19.395	0.0013
C-arginine	0.099	1	0.099	1.224	0.2945
AB	0.777	1	0.777	9.633	0.0112
AC	0.002	1	0.002	0.019	0.8928
BC	0.012	1	0.012	0.148	0.7085
A^∧2	0.134	1	0.134	1.664	0.2260
B^∧2	0.970	1	0.970	12.034	0.0060
C^∧2	1.308	1	1.308	16.241	0.0024
Residual	0.806	10	0.081
Lack of fit	0.793	5	0.159	60.763	<0.0002	Significant
Pure error	0.013	5	0.003
Cor total	8.956	9

Coefficient of determination (𝑅²) = 0.909.