Clinical Study

Effects of Sleep Deprivation on Brain Bioenergetics, Sleep, and Cognitive Performance in Cocaine-Dependent Individuals

Table 2

Polysomnographic assessments of sleep control versus all cocaine-dependent (COC) participants data are displayed as mean (Standard Deviation).

Sig.BaselineSig.RecoverySig.
ControlCOCControlCOC

Sleep onset latency (mins.)23.3 (6.4)34.3 (20.4)10.5 (18.5)4.6 (2.6)*
Waking after sleep onset (mins.)54.9 (18.5)66.5 (32.2)14.7 (2.5)33.0 (9.3)*
Sleep efficiency index81.8 (4.3)79.1 (5.2)94.5 (1.2)91.8 (1.8)*
Total sleep time (hrs.)6.3 (0.3)6.3 (0.4)7.4 (0.2)7.4 (0.1)*
Number of arousals88.9 (10.1)54.5 (6.5)78.2 (8.9)56.0 (7.2)
Arousal index14.5 (2.0)16.9 (7.8)10.4 (1.3)7.1 (1.0)
Stage 1 (mins.)49.1 (8.6)42.5 (3.4)41.4 (8.0)30.7 (5.1)
Stage 2 (mins.)214.5 (12.7)238.1 (19.1)251.8 (11.5)259.4 (7.8)*
Stage 3 (mins.)27.7 (7.5)16.7 (7.0)32.7 (11.9)18.3 (6.7)
Stage 4 (mins.)8.5 (4.4)7.2 (4.0)16.9 (6.9)12.9 (8.5)
REM (mins.)79.4 (8.8)74.3 (8.7)101.3 (5.7)121.8 (9.2)*
Slow wave sleep (mins.)132.9 (34.6)95.7 (36.5)216.0 (50.6)143.2 (57.6)

Significance (Sig.): *sleep night ; group .