Effect of Electroacupuncture on Rats with Chronic Constriction Injury-Induced Neuropathic Pain

Table 2

Effect of electroacupuncture (EA) on cold plate lift leg test at 4°C in SD rats with chronic constriction injury (CCI)-induced neuropathic pain (counts).

	Normal	Control	Sham	2EA	15EA
D5	0.22 ± 0.67	24.67 ± 5.27*	26.00 ± 4.74*	22.89 ± 3.10*	26.11 ± 3.76*
D6	0.11 ± 0.33	27.78 ± 8.74*	24.78 ± 7.22*	15.22±3.70^∗#¶	13.56±5.13^∗#¶
D7	0.11 ± 0.33	26.00 ± 8.53*	25.78 ± 7.79*	13.22±6.57^∗#¶	14.33±4.85^∗#¶
D8	0.00 ± 0.00	27000 ± 8.44*	26.33 ± 6.61*	13.56±4.10^∗#¶	14.44±3.24^∗#¶
D11	0.11 ± 0.33	32.11 ± 7.83*	29.56 ± 8.65*	16.89±7.29^∗#¶	16.67±7.33^∗#¶
D12	0.00 ± 0.00	32.33 ± 6.82*	32.00 ± 9.34*	14.44±6.42^∗#¶	14.67±6.40^∗#¶
D13	0.00 ± 0.00	29.33 ± 6.60*	30.89 ± 10.18*	14.78±8.24^∗#¶	17.44±7.84^∗#¶

Data represent mean ± standard deviation. 𝑁=9; normal: normal group, no CCI, no EA; control: control group, CCI without EA; sham: sham group, CCI with sham EA; 2EA: 2EA group, CCI with 2 Hz EA on ipsilateral Zusanli and Shangjuxu acupoints; 15EA: 15EA group, CCI with 15 Hz EA on ipsilateral Zusanli and Shangjuxu acupoints; D5: 5th day following ligation; D6: 6th day following ligation; D7: 7th day following ligation; D8: 8th day following ligation; D11: 11th day following ligation; D12: 12th day following ligation; D13: 13th day following ligation; *P < .001 compared with normal’; ^#P < 0.001 compared with control; ¶P < .001 compared with sham.