Using Targeted Virotherapy to Treat a Resistant Ewing Sarcoma Model: From the Bedside to the Bench and Back

Table 1

VSVΔM51 infects multiple types of ex vivo human sarcomas. Approximately 50% of the ex vivo specimens tested are susceptible to VSVΔM51 infection.

Sarcoma type	No. of biopsy samples	Susceptible to VSVΔM51	%
Malignant fibrohistiocytoma	17	11	65
Osteosarcoma	14	9	64
Liposarcoma	13	4	31
Chondrosarcoma	5	4	80
Fibrosarcoma	4	1	25
Synovial sarcoma	3	2	67
Ewing’s sarcoma	3	2	67
Dermatofibrosarcoma protuberans	1	1	100
Neuroblastoma	1	0	0
Hemangiopericytoma	1	1	100
Peripheral nerve sheath tumor	1	1	100
Myxoma	2	0	0
Leiomyosarcoma	2	1	50
Chordoma	1	1	100
Total	68	38	56