Research Article
Using Targeted Virotherapy to Treat a Resistant Ewing Sarcoma Model: From the Bedside to the Bench and Back
Table 1
VSVΔM51 infects multiple types of ex vivo human sarcomas. Approximately 50% of the ex vivo specimens tested are susceptible to VSVΔM51 infection.
| Sarcoma type | No. of biopsy samples | Susceptible to VSVM51 | % |
| Malignant fibrohistiocytoma | 17 | 11 | 65 | Osteosarcoma | 14 | 9 | 64 | Liposarcoma | 13 | 4 | 31 | Chondrosarcoma | 5 | 4 | 80 | Fibrosarcoma | 4 | 1 | 25 | Synovial sarcoma | 3 | 2 | 67 | Ewing’s sarcoma | 3 | 2 | 67 | Dermatofibrosarcoma protuberans | 1 | 1 | 100 | Neuroblastoma | 1 | 0 | 0 | Hemangiopericytoma | 1 | 1 | 100 | Peripheral nerve sheath tumor | 1 | 1 | 100 | Myxoma | 2 | 0 | 0 | Leiomyosarcoma | 2 | 1 | 50 | Chordoma | 1 | 1 | 100 |
| Total | 68 | 38 | 56 |
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