The Influence of Monoamine Oxidase Variants on the Risk of Betel Quid-Associated Oral and Pharyngeal Cancer

Figure 2

The mRNA expression of MAO-A after arecoline treatment at different concentrations (0, 50, 100, 200, 400, and 800 μM). (a) Normal human gingival fibroblast cells (HGF). (b) Cancer cells (Ca9-22 cell line). The average fold change (mean ± standard errors (SE)) of the MAO-A gene was measured in triplicate; error bars indicate SE of mean. Multiple comparisons of mean MAO-A expression were analyzed by one-way ANOVA, and a post hoc comparison was performed by Tukey’s HSD test. The value for the trend is presented, and an asterisk () indicates a statistically significant difference () compared with cells without treatment.

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