The Influence of Monoamine Oxidase Variants on the Risk of Betel Quid-Associated Oral and Pharyngeal Cancer

<div>The mRNA expression of MAO-A and MAO-B in human oral tumor (T) tissues compared with their adjacent normal (N) tissues. The relative fold change was estimated by the formula <svg height="12.4706pt" id="M19" style="vertical-align:-0.04979992pt" version="1.1" viewbox="-0.0498162 -12.4208 36.3674 12.4706" width="36.3674pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0135,0,0,-0.0135,0,0)"><path d="M412 140C382 77 369 73 315 73H129L270 222C362 320 402 379 402 466C402 571 322 635 234 635C177 635 130 609 99 576L42 495L64 475C90 514 133 568 201 568C274 568 318 519 318 435C318 349 255 267 193 193C144 135 87 78 32 23V0H405C417 45 427 89 440 131L412 140Z" id="g113-51"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g><g transform="matrix(.0095,0,0,-0.0095,6.503,-5.984)"><path d="M556 236V289H56V236H556Z" id="g54-33"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="611" vert-adv-y="611"></glyph.data></g><g transform="matrix(.0095,0,0,-0.0095,12.298,-5.984)"><path d="M610 0V27L347 666L316 657L46 26V0H610ZM504 54H116L310 537L504 54Z" id="g50-133"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="654" vert-adv-y="654"></glyph.data></g><g transform="matrix(.0095,0,0,-0.0095,18.496,-5.984)"><path d="M610 0V27L347 666L316 657L46 26V0H610ZM504 54H116L310 537L504 54Z" id="g50-133"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="654" vert-adv-y="654"></glyph.data></g><g transform="matrix(.0095,0,0,-0.0095,24.693,-5.984)"><path d="M690 629C653 643 577 667 483 667C225 667 24 528 24 292C24 92 174 -17 367 -17C448 -17 534 1 570 10C592 34 642 131 658 174C648 180 639 186 629 192C562 89 499 21 382 21C223 21 130 138 130 298C130 467 255 627 462 627C582 627 643 589 650 462L686 466C689 517 688 580 690 629Z" id="g50-68"></path><glyph.data ascent="3443" descent="-2856" horiz-adv-x="714" vert-adv-y="714"></glyph.data></g><g transform="matrix(.0068,0,0,-0.0068,31.066,-3.794)"><path d="M575 299C575 406 528 454 412 454C385 454 342 447 313 440L330 514L318 525C293 510 258 487 242 466L227 419C194 403 158 384 123 361L126 327C155 342 183 355 220 364L107 -148C96 -198 76 -210 19 -215L14 -253L259 -241V-206L240 -205C184 -202 183 -188 192 -141L220 -1C242 -10 269 -12 284 -12C352 5 434 48 484 102C542 165 575 238 575 299ZM479 290C479 170 380 41 305 41C281 41 249 60 237 72L300 395C329 399 353 401 374 401C426 401 479 377 479 290Z" id="g176-113"></path><glyph.data ascent="3439" descent="-2858" horiz-adv-x="600" vert-adv-y="600"></glyph.data></g></svg> compared with adjacent tissue (<svg height="9.21094pt" id="M20" style="vertical-align:-0.2129908pt" version="1.1" viewbox="-0.0498162 -8.99795 33.5893 9.21094" width="33.5893pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0135,0,0,-0.0135,0,0)"><path d="M822 650H589L583 622C660 617 677 607 674 561C672 534 664 481 647 390L600 137H596L273 650H126L120 622C176 620 194 615 207 594C221 571 225 557 214 504L161 257C141 166 129 112 121 85C108 42 83 30 29 28L23 0H260L266 28C193 33 173 42 176 89C178 122 186 172 202 255L256 527H259L583 -8H612L690 390C708 481 720 535 728 558C744 603 756 619 816 622L822 650Z" id="g113-79"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="839" vert-adv-y="839"></glyph.data></g><g transform="matrix(.0135,0,0,-0.0135,15.155,0)"><path d="M535 323V373H52V323H535ZM535 138V188H52V138H535Z" id="g117-34"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="587" vert-adv-y="587"></glyph.data></g><g transform="matrix(.0135,0,0,-0.0135,26.893,0)"><path d="M137 343C167 482 260 545 321 574C357 591 397 603 429 609L423 641C382 634 335 622 295 608C189 570 37 457 37 238C37 84 125 -12 242 -12C362 -12 447 89 447 209C447 311 374 393 267 393C247 393 226 386 204 376L137 343ZM227 337C318 337 361 256 361 173C361 105 336 22 258 22C176 22 126 120 126 240C126 266 127 291 132 310C155 323 189 337 227 337Z" id="g113-55"></path><glyph.data ascent="3473" descent="-2876" horiz-adv-x="480" vert-adv-y="480"></glyph.data></g></svg>).</div>

The Scientific World Journal

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Figure 3

Figure 3: The Influence of Monoamine Oxidase Variants on the Risk of Betel Quid-Associated Oral and Pharyngeal Cancer 