Effect of Vetiveria zizanioides Essential Oil on Melanogenesis in Melanoma Cells: Downregulation of Tyrosinase Expression and Suppression of Oxidative Stress

Table 1

GC-MS analysis of the essential oil from Vetiveria zizanioides (VZ-EO).

Compound	Rt	KI	Area (%)	M.f.
2,3,5,5,8,8-Hexamethyl-cycloocta-1,3,6-triene	23.19	1314	2.28	C14H22
1,5,9,9-Tetramethyl-2-methylene-spiro[3.5]non-5-ene	24.08	1328	3.96	C14H22
(+)-Sativen	25.51	1339	2.83	C15H24
4,8,8-Trimethyl-2-methylene-4-vinylbicyclo[5.2.0]nonane	25.62	1407	4.53	C15H24
α-Amorphene	26.05	1440	7.80	C15H24
2-Isopropenyl-1,3,5-trimethylbenzene	26.14	1465	2.43	C12H16
α-Gurjunene	26.22	1479	5.91	C15H24
β-Vatirenene	26.30	1489	5.94	C15H22
δ-Cadinene	26.55	1499	2.57	C15H24
β-Guaiene	26.93	1523	4.28	C15H24
Dehydroaromadendrene	27.05	1545	5.45	C15H22
Cubenol	28.82	1580	2.09	C15H26O
(+)-Ledene	29.28	1605	4.77	C15H24
Epiglobulol	29.42	1632	2.21	C15H26O
Widdrol	29.90	1651	2.13	C15H26O
6-Isopropenyl-4,8a-dimethyl-1,2,3,5,6,7,8,8a-octahydro-naphthalen-2-ol	30.04	1690	1.97	C15H24O
3-(2-Isopropyl-5-methylphenyl)-2-methylpropionic acid	30.17	1745	3.17	C14H20O2
Cedr-8-en-13-ol	30.67	1769	12.36	C15H24O
Ethyl 4-(4-methylphenyl)-4-pentenoate	31.06	1804	2.12	C16H20O3
Isovellerdiol	31.11	1842	2.38	C15H24O2
α-Curcumene	31.16	1867	2.44	C15H22
3,3,8,8-Tetramethyl-tricyclo[5.1.0.0(2,4)]oct-5-ene-5-propanoic acid	31.38	1890	4.82	C15H22O2
Solavetivone	31.46	1906	4.20	C15H22O
3,8-Dimethyl-4-(1-methylethylidene)-2,4,6,7,8,8a-hexahydro-5(1H)-azulenone	31.82	1925	4.89	C15H22O
(−)-Spathulenol	31.88	1938	2.47	C15H24O

Rt: retention time (min); KI: Kovats index; M.f.: molecular formula.