Research Article
Preparation and Evaluation of Novel In Situ Gels Containing Acyclovir for the Treatment of Oral Herpes Simplex Virus Infections
Table 5
Evaluation data 2 of in situ gel formulation.
| FC | Viscosity (Cp) | Solution state | Gel state | Spreadability | Gel strength |
| Ft1 | 98.93 ± 0.40 | 1481.33 ± 6.80 | 6.63 ± 0.15 | 4.67 ± 0.57 | Ft2 | 104.88 ± 2.29 | 1540.67 ± 15.65 | 6.43 ± 0.05 | 5.66 ± 0.57 | Ft3 | 149.10 ± 2.73 | 1505.00 ± 6.00 | 5.70 ± 0.17 | 21.33 ± 1.53 | Ft4 | 111.61 ± 10.67 | 1564.00 ± 7.21 | 5.66 ± 0.12 | 23.66 ± 0.57 | Ft5 | 158.27 ± 6.68 | 1498.67 ± 14.22 | 5.26 ± 0.11 | 80.33 ± 0.57 | Ft6 | 199.74 ± 0.63 | 1594.33 ± 12.89 | 4.53 ± 0.12 | 99.66 ± 0.57 | Fg1 | 214.41 ± 3.08 | 1493.67 ± 5.03 | 6.56 ± 0.05 | 10.33 ± 1.52 | Fg2 | 220.47 ± 2.16 | 1495.67 ± 6.65 | 6.30 ± 0.02 | 13.66 ± 1.52 | Fg3 | 242.05 ± 2.16 | 1533.67 ± 19.50 | 5.66 ± 0.20 | 26.33 ± 1.52 | Fg4 | 263.60 ± 10.58 | 1586.33 ± 5.50 | 5.03 ± 0.15 | 65.66 ± 1.15 | Fg5 | 242.50 ± 14.90 | 1535.33 ± 11.01 | 5.23 ± 0.05 | 89.33 ± 0.57 | Fg6 | 344.87 ± 5.56 | 1621.33 ± 3.21 | 4.46 ± 0.05 | 119.3 ± 1.52 |
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The bold data refer to four selected formulations with the best results.
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