RRHGE: A Novel Approach to Classify the Estrogen Receptor Based Breast Cancer Subtypes

Table 2

RRHGE gene signature size.

Training; set	ER+	ER−
	Subnetwork list; (no. of subnetworks)	Subnetwork list; (no. of subnetworks)
Grade 1	45	31
Grade 2	35	37
Grade 3	39	34
Final gene; signature set	326	145

Our gene signature set consists of 471 genes that compose 326 genes for the ER+ subtype and 145 genes for the ER− subtype.