RRHGE: A Novel Approach to Classify the Estrogen Receptor Based Breast Cancer Subtypes

Table 3

Regression coefficients of μ (𝛽₁) and 𝜎 (𝛽₂) in each of the six training sets, respectively.

Training set	𝛽0^∗	𝛽1	𝛽2	𝑃 value
ER+ (Grade 1)	−8.06𝐸−16	0.4601	0.7066	<0.001
ER+ (Grade 2)	3.64𝐸−15	0.4878	0.6846	<0.001
ER+ (Grade 3)	9.81𝐸−16	0.4650	0.7094	<0.001
ER− (Grade 1)	1.49𝐸−15	0.4273	0.7274	<0.001
ER− (Grade 2)	−2.68𝐸−15	0.4484	0.7199	<0.001
ER− (Grade 3)	1.20𝐸−15	0.4673	0.7078	<0.001

∗Here, 𝛽₀ in each training set represents very small value and so assigned 𝛽₀ as zero.