Research Article

Exploration of Potential Roles of a New LOXL2 Splicing Variant Using Network Knowledge in Esophageal Squamous Cell Carcinoma

Figure 1

DEGs were mapped to the HPRD&BioGRID parent PPI network to generate PPI subnetworks. (a) PPI subnetworks of LOXL2-e13-DEGs. (b) PPI subnetworks of LOXL2-WT-DEGs. (c) Interactions between LOXL2-e13-DEGs. (d) Interactions between LOXL2-WT- DEGs. Nodes are labeled by different colors to indicate the expression trend of proteins. Green nodes represent proteins encoded by downregulated genes, while red nodes represent proteins encoded by upregulated genes. Interacting proteins without significantly different expression are represented as blue nodes.
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