Exploration of Potential Roles of a New LOXL2 Splicing Variant Using Network Knowledge in Esophageal Squamous Cell Carcinoma
Figure 4
Prioritization analyses of e13-WT-DEGs based on the PPI subnetwork. (a) PPI subnetwork of e13-WT-DEGs. (b) Random Walk with Restart algorithm was used to score all proteins in the PPI network with LOXL2 set as the seed node. The size of each node in the PPI subnetwork was designed as a gradient based on the scores. (c) The e13-WT-DEGs were extracted from (b) to illustrate their sizes. (d) The DEGs were rearranged according to their closeness to LOXL2-e13 protein.
