Clinical Study

Biochemical Characterization of Early Osteoarthritis in the Ankle

Figure 1

Increasing intra-articular levels of aggrecan are observed with progress of OA measured by radiological changes of the ankle (Kellgren Lawrence Score). Results of the polynomial regression analysis, the Spearman correlation, and the post hoc statistics (Kruskal-Wallis H-Test) are indicated for absolute aggrecan levels and concentrations in relation to the total protein content (TPC) on the bottom. Polynomial regression with degree of 2 gives an for absolute and for relative concentrations; values are shown with ±SEM.
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