Anthelmintic Activity of Crude Extract and Essential Oil of Tanacetum vulgare (Asteraceae) against Adult Worms of Schistosoma mansoni

Table 1

In vitro effects of crude hydroalcoholic extract (TV) and essential oil of T. vulgare (TV-EO) against S. mansoni adult worms.

Groups	Incubation period (h)	Separated worms (%)^a	Dead worms (%)^a	Decrease in motor activity (%)^a		Worms with tegumental alteration (%)^a
				Slight	Significant	Partial	Extensive
Control^b	24	0	0	0	0	0	0
	72	0	0	0	0	0	0
0.5% DMSO	24	0	0	0	0	0	0
	72	0	0	0	0	0	0
PZQ^c	24	0	100	0	100	0	100
	72	0	100	0	100	0	100
TV
10 𝜇g/mL	24	0	0	0	0	0	0
	72	0	0	0	0	0	0
50 𝜇g/mL	24	0	0	0	0	0	0
	72	0	100	0	100	0	100
100 𝜇g/mL	24	0	0	0	0	0	0
	72	100	100	0	100	100	100
200 𝜇g/mL	24	0	100	0	100	0	100
	72	100	100	0	100	0	100
TV-EO
10 𝜇g/mL	24	0	0	0	0	0	0
	72	50	0	0	100	0	0
50 𝜇g/mL	24	0	0	0	0	0	0
	72	100	0	0	100	0	0
100 𝜇g/mL	24	100	0	0	0	0	0
	72	100	0	0	100	0	0
200 𝜇g/mL	24	100	100	0	100	0	0
	72	100	100	0	100	0	0

aPercentages relative to the 20 worms investigated. bRPMI 1640. cTested at concentration of 10 𝜇M.