Research Article
Anthelmintic Activity of Crude Extract and Essential Oil of Tanacetum vulgare (Asteraceae) against Adult Worms of Schistosoma mansoni
Table 1
In vitro effects of crude hydroalcoholic extract (TV) and essential oil of T. vulgare (TV-EO) against S. mansoni adult worms.
| Groups | Incubation period (h) |
Separated worms (%)a | Dead worms (%)a | Decrease in motor activity (%)a | Worms with tegumental alteration (%)a | Slight | Significant | Partial | Extensive |
| Controlb | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 72 | 0 | 0 | 0 | 0 | 0 | 0 | 0.5% DMSO | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 72 | 0 | 0 | 0 | 0 | 0 | 0 | PZQc | 24 | 0 | 100 | 0 | 100 | 0 | 100 | 72 | 0 | 100 | 0 | 100 | 0 | 100 | TV | | | | | | | | 10 g/mL | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 72 | 0 | 0 | 0 | 0 | 0 | 0 | 50 g/mL | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 72 | 0 | 100 |
0 | 100 | 0 | 100 | 100 g/mL | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 72 | 100 | 100 | 0 | 100 | 100 | 100 | 200 g/mL | 24 | 0 | 100 | 0 | 100 | 0 | 100 | 72 | 100 | 100 | 0 | 100 | 0 | 100 | TV-EO | | | | | | | | 10 g/mL | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 72 | 50 | 0 | 0 | 100 | 0 | 0 | 50 g/mL | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 72 | 100 | 0 | 0 | 100 | 0 | 0 | 100 g/mL | 24 | 100 | 0 | 0 | 0 | 0 | 0 | 72 | 100 | 0 | 0 | 100 | 0 | 0 | 200 g/mL | 24 | 100 | 100 | 0 | 100 | 0 | 0 | 72 | 100 | 100 | 0 | 100 | 0 | 0 |
|
|
Percentages relative to the 20 worms investigated. RPMI 1640. Tested at concentration of 10 M.
|