Tinzaparin Provides Lower Lipid Profiles in Maintenance Hemodialysis Patients: A Cross-Sectional Observational Study
Table 1
Demographic and clinical data stratified according to the use of tinzaparin and unfractionated heparin.
Variables
All ()
UFH ()
Tinzaparin ()
value
Age (y)
65.0 ± 13.2
65.4 ± 13.2
62.0 ± 13.0
0.95
Male (%)
210 (48.4%)
192 (49.7%)
18 (37.5%)
0.11
Body mass index (kg/m2)
22.6 ± 3.7
22.5 ± 3.7
23.0 ± 3.8
0.399
HD duration (months)
93.0 ± 68.8
88.1 ± 67.4
133 ± 66.7
<0.001
Artificial kidney
0.491
Polysulfone (%)
267 (61.5%)
234 (60.6%)
33 (68.7%)
PMMA (%)
121 (27.9%)
111 (28.7%)
10 (20.8%)
Cellulose citrate (%)
46 (10.6%)
41 (10.6%)
5 (10.4%)
Diabetes mellitus (%)
177 (40.8%)
163 (42.2%)
14 (29.1%)
0.082
SBP (mmHg)
142.8 ± 25.9
142.8 ± 26.0
142.9 ± 24.5
0.984
DBP (mmHg)
80.9 ± 62.6
81.2 ± 66.1
78.38 ± 16.9
0.770
Lipid-lowering agent (%)
68 (15.7%)
58 (15%)
10 (20.8%)
0.290
Kt/V
1.39 ± 0.19
1.38 ± 0.2
1.4 ± 0.2
0.060
iPTH (pg/mL)
261 ± 304
249± 307
341 ± 260
0.053
Hemoglobin (g/dL)
10.3 ± 1.2
10.3 ± 1.3
10.5 ± 1.3
0.212
Albumin (g/dL)
4.2 ± 0.4
4.2 ± 0.4
4.2 ± 0.4
0.353
AST (IU/L)
20.1 ± 23.3
20.5 ± 24.6
17.2 ± 5.8
0.357
ALT (IU/L)
21.2 ± 31.0
21.5 ± 32.7
18.9 ± 9.8
0.584
Iron (μg/dL)
65.3 ± 23.5
65.6 ± 23.3
58.4 ± 17.9
0.057
Ferritin (μg/dL)
602 ± 468
621 ± 500
471 ± 237
0.044
TIBC (μg/dL)
211 ± 41
210 ± 41
217 ± 40
0.219
Total-bilirubin (mg/dL)
0.32 ± 0.2
0.33 ± 0.26
0.27 ± 0.09
<0.001
Alk-p (mg/dL)
92.8 ± 71.4
93.4 ± 74.1
88.3 ± 43.6
0.640
Uric acid (mg/dL)
6.9 ± 1.3
6.8 ± 1.3
7.0 ± 1.2
0.274
Sodium (meq/L)
139.3 ± 3.2
139.1 ± 3.3
140.3 ± 2.8
0.017
Potassium (meq/L)
4.6 ± 0.7
4.6 ± 0.7
4.7 ± 0.6
0.515
Ionized calcium (mg/dL)
4.9 ± 0.5
4.9 ± 0.5
5.1 ± 0.5
0.023
Phosphate (mg/dL)
5.1 ± 1.4
5.1 ± 1.4
5.23 ± 1.1
0.459
Values for continuous variables are expressed as mean ± standard deviation; values for categorical variables are given as a number (percentage). UFH: unfractionated heparin; HD: hemodialysis; PMMA: polymethylmethacrylate; SBP: systolic blood pressure; DBP: diastolic blood pressure; iPTH: intact parathyroid hormone; AST: aspartate aminotransferase; ALT: alanine aminotransferase; TIBC: total iron-binding capacity; Alk-p: alkaline phosphatase.
