Inhibitory Effect of Cinobufagin on L-Type C Currents, Contractility, and C Homeostasis of Isolated Adult Rat Ventricular Myocytes

Figure 7

Effects of CBG on Ca²⁺ transients and cell shortening in isolated rat ventricular myocytes. (a) Actual tracings of effects of 10⁻⁸ M CBG in a myocyte. (b) Individual signals of fura-2 ratio (upper tracings) and cell shortening (lower tracings). Individual tracings were obtained by averaging five successive signals. (c) Summarized data on effects of 10⁻⁸ M CBG on fura-2 ratio and cell shortening. Data are presented as means ± S.E.M. (𝑛=7–12 cells). ^∗∗∗𝑃<0.001, compared with control.

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