Inhibitory Effect of Cinobufagin on L-Type C<svg  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.2452002pt" id="M1" height="16.138pt" version="1.1" viewBox="-0.0657574 -15.8928 21.8002 16.138" width="21.8002pt"><g transform="matrix(.018,0,0,-0.018,0,0)"><path id="g190-98" d="M433 39L423 65C413 59 399 54 387 54C370 54 352 69 352 114V299C352 352 342 392 307 422C285 440 255 449 225 449C168 437 102 399 75 379C56 365 44 353 44 339C44 315 69 296 87 296C101 296 111 303 116 319C124 349 133 371 145 385C156 397 171 404 190 404C241 404 275 364 275 291V274C253 256 180 229 120 209C65 190 39 159 39 110C39 47 88 -12 159 -12C189 -12 237 25 277 52C282 35 288 21 301 8C312 -3 333 -12 348 -12L433 39ZM275 84C256 65 221 48 195 48C164 48 124 73 124 124C124 161 146 180 185 198C206 208 254 229 275 240V84Z"/><glyph.data ascent="989" descent="-360" horiz-adv-x="439" vert-adv-y="439"/></g><g transform="matrix(.013,0,0,-0.013,7.88,-7.899)"><path id="g190-243" d="M411 139C381 76 368 73 314 73H129L267 224C351 317 400 380 400 469C400 574 322 635 233 635C176 635 128 610 98 576L40 495L63 476C89 515 130 568 198 568C274 568 316 519 316 436C316 347 251 264 191 192C142 134 85 76 30 21V0H403C415 45 425 89 438 131L411 139Z"/><glyph.data ascent="989" descent="-360" horiz-adv-x="465" vert-adv-y="465"/></g><g transform="matrix(.013,0,0,-0.013,13.702,-7.899)"><path id="g190-44" d="M529 230V280H320V487H262V280H52V230H262V0H320V230H529Z"/><glyph.data ascent="989" descent="-360" horiz-adv-x="580" vert-adv-y="580"/></g></svg> Currents, Contractility, and C<svg  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.2452002pt" id="M2" height="16.138pt" version="1.1" viewBox="-0.0657574 -15.8928 21.8002 16.138" width="21.8002pt"><g transform="matrix(.018,0,0,-0.018,0,0)"><use xlink:href="#g190-98"/><glyph.data ascent="989" descent="-360" horiz-adv-x="439" vert-adv-y="439"/></g><g transform="matrix(.013,0,0,-0.013,7.88,-7.899)"><use xlink:href="#g190-243"/><glyph.data ascent="989" descent="-360" horiz-adv-x="465" vert-adv-y="465"/></g><g transform="matrix(.013,0,0,-0.013,13.702,-7.899)"><use xlink:href="#g190-44"/><glyph.data ascent="989" descent="-360" horiz-adv-x="580" vert-adv-y="580"/></g></svg> Homeostasis of Isolated Adult Rat Ventricular Myocytes

<table>Summarized data for the effect of CBG on Tp and Tr for myocyte shortening. Changes in timing were measured in milliseconds and normalized to changes in the peak amplitude. Data are presented as means ± S.E.M. (<svg height="10.925" id="M111" style="vertical-align:-0.10033pt" version="1.1" viewbox="0 0 36.237499 10.925" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>, compared with control.</table>

The Scientific World Journal

fig8

Figure 8

Figure 8: Inhibitory Effect of Cinobufagin on L-Type C<svg  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.2452002pt" id="M1" height="16.138pt" version="1.1" viewBox="-0.0657574 -15.8928 21.8002 16.138" width="21.8002pt"><g transform="matrix(.018,0,0,-0.018,0,0)"><path id="g190-98" d="M433 39L423 65C413 59 399 54 387 54C370 54 352 69 352 114V299C352 352 342 392 307 422C285 440 255 449 225 449C168 437 102 399 75 379C56 365 44 353 44 339C44 315 69 296 87 296C101 296 111 303 116 319C124 349 133 371 145 385C156 397 171 404 190 404C241 404 275 364 275 291V274C253 256 180 229 120 209C65 190 39 159 39 110C39 47 88 -12 159 -12C189 -12 237 25 277 52C282 35 288 21 301 8C312 -3 333 -12 348 -12L433 39ZM275 84C256 65 221 48 195 48C164 48 124 73 124 124C124 161 146 180 185 198C206 208 254 229 275 240V84Z"/><glyph.data ascent="989" descent="-360" horiz-adv-x="439" vert-adv-y="439"/></g><g transform="matrix(.013,0,0,-0.013,7.88,-7.899)"><path id="g190-243" d="M411 139C381 76 368 73 314 73H129L267 224C351 317 400 380 400 469C400 574 322 635 233 635C176 635 128 610 98 576L40 495L63 476C89 515 130 568 198 568C274 568 316 519 316 436C316 347 251 264 191 192C142 134 85 76 30 21V0H403C415 45 425 89 438 131L411 139Z"/><glyph.data ascent="989" descent="-360" horiz-adv-x="465" vert-adv-y="465"/></g><g transform="matrix(.013,0,0,-0.013,13.702,-7.899)"><path id="g190-44" d="M529 230V280H320V487H262V280H52V230H262V0H320V230H529Z"/><glyph.data ascent="989" descent="-360" horiz-adv-x="580" vert-adv-y="580"/></g></svg> Currents, Contractility, and C<svg  xmlns:xlink="http://www.w3.org/1999/xlink" xmlns="http://www.w3.org/2000/svg" style="vertical-align:-0.2452002pt" id="M2" height="16.138pt" version="1.1" viewBox="-0.0657574 -15.8928 21.8002 16.138" width="21.8002pt"><g transform="matrix(.018,0,0,-0.018,0,0)"><use xlink:href="#g190-98"/><glyph.data ascent="989" descent="-360" horiz-adv-x="439" vert-adv-y="439"/></g><g transform="matrix(.013,0,0,-0.013,7.88,-7.899)"><use xlink:href="#g190-243"/><glyph.data ascent="989" descent="-360" horiz-adv-x="465" vert-adv-y="465"/></g><g transform="matrix(.013,0,0,-0.013,13.702,-7.899)"><use xlink:href="#g190-44"/><glyph.data ascent="989" descent="-360" horiz-adv-x="580" vert-adv-y="580"/></g></svg> Homeostasis of Isolated Adult Rat Ventricular Myocytes 

The Scientific World Journal

Inhibitory Effect of Cinobufagin on L-Type C Currents, Contractility, and C Homeostasis of Isolated Adult Rat Ventricular Myocytes

Figure 8