Evaluation on Genotoxicity and Teratogenicity of Aqueous Extract from Cyclocarya paliurus Leaves

Table 4

Effect of Cyclocarya paliurus leaf aqueous extract on the rate of mouse sperm abnormality. Data are expressed as mean ± SD.

Dose/(g/kg·bw)	Mice number	Tested sperms	Abnormal sperms	Abnormality incidence	Constituent of different abnormal sperms/%
					Lack hook	Banana-like	Fat-head	Morphism	Folding-tail	Double-headed	Twin-tailed
10.0	5	5000	114	2.28±0.41	30.7	14.9	15.8	38.6	0.0	0.0	0.0
5.0	5	5000	106	2.12±0.52	33.0	7.5	17.9	41.5	0.0	0.0	0.0
2.5	5	5000	111	2.22±0.31	32.4	10.8	13.5	43.2	0.0	0.0	0.0
Negative; controls	5	5000	109	2.18±0.53	33.0	7.3	19.3	40.4	0.0	0.0	0.0
Positive; controls	5	5000	462	9.24±0.90	28.6	19.5	21.0	30.3	0.0	0.0	0.6

Compared to negative controls; 𝑃>0.05. Compared to positive controls; 𝑃<0.01.