Research Article

Protein-Protein Interactions Prediction Based on Iterative Clique Extension with Gene Ontology Filtering

Figure 2

An illustration of mining cliques based on predicted protein pairs. (a) Components of intersection between the neighbors of node 1 and node 2 are candidates to form 3 cliques. (b) Node 3 derived from with nodes 1 and 2 forms 3 cliques. The neighbors of node 3 intersect and construct the candidate set of 4 cliques. (c) The node in the composes of nodes 1, 2, and 3 to form 4 cliques. The neighbors of node 4 derived from intersect and construct the candidate set for forming 5 cliques. This procedure is repeated until the maximum clique is found based on node 1 and node 2.
523634.fig.002a
(a)
523634.fig.002b
(b)
523634.fig.002c
(c)