Formulation and Evaluation of Guggul Lipid Nanovesicles for Transdermal Delivery of Aceclofenac

Table 2

Physicochemical evaluation of developed nanovesicle formulations.

Formulation code	Size* (nm)	PDI*	𝜁 potential* (mV)	Entrapment efficiency* (%)	Viscosity^† (Cps)
PC-1	147±2.5	0.297±0.001	−42±1.2	47.6±1.8	17760±5.84
PC-2	136±1.6	0.289±0.003	−40±1	34.2±1.4	17617±4.86
PC-3	129±2.4	0.265±0.007	−39±0.8	26.3±2.6	17264±4.98
GL-1	121±1.1	0.153±0.004	−25±1.1	78.9±1.1	18321±3.65
GL-2	114±1.3	0.143±0.008	−19±1.3	67.7±3.1	18102±2.79
GL-2	103±3.5	0.132±0.002	−16±1.9	53.4±1.2	17745±3.23

All data expressed as mean ± S.D.; 𝑛=3; 𝑃≤0.05.