Progesterone Increases Apoptosis and Inversely Decreases Autophagy in Human Hepatoma HA22T/VGH Cells Treated with Epirubicin

Figure 1

Effects of epirubicin on cell growth without or with progesterone addition. HA22T/VGH cells were treated with different concentrations of epirubicin without or with 30 μM progesterone for 24 h (a) or 48 h (b). Results are expressed as the mean ± standard deviation (S.D.) for three separate experiments. E: epirubicin; P30: 30 μM progesterone. ^∗𝑃<0.05 compared to the corresponding untreated controls. ^#𝑃<0.05 compared to the corresponding epirubicin-treated group.

(a)

(b)