Progesterone Increases Apoptosis and Inversely Decreases Autophagy in Human Hepatoma HA22T/VGH Cells Treated with Epirubicin
Figure 6
Epirubicin and/or progesterone effect on MRP-1 expression. HA22T/VGH cells were treated with epirubicin and/or progesterone for 6, 12, or 24 h, and then MRP-1 mRNA was analyzed by RT-PCR. The MRP-1 mRNA expression was normalized to GAPDH mRNA. The density of band was expressed as the relative density compared to that in untreated cells (control), taken as 100%. Results are expressed as the mean ± standard deviation (S.D.) for three separate experiments. C: untreated cells, E0.3: 0.3 μM epirubicin, and P30: 30 μM progesterone. compared to the untreated controls. # compared to epirubicin-treated group.
