Oral Complications and Management Strategies for Patients Undergoing Cancer Therapy

Table 2

A summary of mucosatoxic chemotherapy agents (data adapted from Köstler et al., 2001 [46], and Saadeh, 2005 [47]).

Category	Drugs
Alkylating agents	Busulfan, carmustine, chlorambucil, cisplatin, cyclophosphamide, dacarbazine, estramustine, ifosfamide, lomustine, mechlorethamine, melphalan, oxaliplatin, procarbazine, and thiotepa
Anthracyclines	Daunorubicin, doxorubicin, epirubicin, idarubicin, and mitoxantrone
Antimetabolites	Capecitabine, cytarabine, floxuridine, 5-fluorouracil, hydroxyurea, 6-mercaptopurine, methotrexate, pemetrexed, and 6-thioguanine
Antitumor antibiotics	Actinomycin d, amsacrine, bleomycin, mithramycin, mitomycin, and plicamycin
Natural products	Etoposide, irinotecan, and streptozotocin
Taxanes	Docetaxel and paclitaxel
Vinca alkaloids	Vinblastine, vincristine, vindesine, and vinorelbine
Others	Carboplatin, fludarabine, gemcitabine, interferons, interleukin-2, mitotane, and topotecan