Aspect of Thrombolytic Therapy: A Review

Table 1

Generation of thrombolytic drug	Fibrin specific	Nonfibrin specific
First	⋯	Urokinase^*
	⋯	Streptokinase^*
Second	Recombinant tissue; plasminogen activator^* (t-PA)	Prourokinase; (scum-PA)
	Alteplase	Sk-plasminogen; activating complex^* (APSAC)
Third	Tenecteplase^* (TNK-tPA)	⋯
	Reteplase^*	⋯
	Monteplase	⋯
	Lanoteplase	⋯
	Pamiteplase	⋯

Approved for clinical use.