Identification of p53 and Its Isoforms in Human Breast Carcinoma Cells
Figure 1
p53 immunohistochemical staining in normal breast tissue and breast cancer. (a) No p53 immunoreactivity was observed in the normal breast cells. (b) A mutant case with strongly positive nuclear staining. Positive p53 immunoreaction in the tumor area is indicated by brown color. Negative nuclei show only the counterstain, indicated by the blue color. Immunostaining was performed with the mouse anti-human p53 monoclonal antibody DO-7. (Immunoperoxidase staining with nuclear counterstain with hematoxylin. Magnification: ×63.)
