Blood Transfusions in Total Hip and Knee Arthroplasty: An Analysis of Outcomes

Table 4

This table shows the unadjusted and adjusted logistic regression analyses measuring the association of use of transfusion, age, and presence of comorbidities with various outcomes.

Effect	Outcome
	Combined complications	Cardiac complications	Pulmonary complications	Renal failure	ICU utilization	30-Day mortality
	Odds ratio (95% CI)	Odds ratio (95% CI)	Odds ratio (95% CI)	Odds ratio (95% CI)	Odds ratio (95% CI)	Odds ratio (95% CI)
Transfusion (unadjusted)	1.86 (1.83–1.90)*	1.49 (1.45–1.53)*	2.46 (2.36–2.57)*	3.40 (3.26–3.56)*	1.76 (1.70–1.82)*	2.41 (2.08–2.78)*
Transfusion	1.65 (1.62–1.69)*	1.28 (1.25–1.32)*	2.29 (2.19–2.40)*	3.22 (3.08–3.38)*	1.78 (1.72–1.84)*	1.74 (1.50–2.03)*
Age group (ref: ≤45 years)
45–54	1.23 (1.14–1.33)*	1.68 (1.42–1.99)*	1.21 (1.00–1.45)**	1.37 (1.10–1.72)**	1.08 (0.97–1.21)	1.82 (0.76–4.33)
55–64	1.78 (1.65–1.92)*	3.29 (2.80–3.87)*	1.50 (1.26–1.78)*	2.04 (1.65–2.52)*	1.11 (1.00–1.24)***	2.42 (1.05–5.56)***
65–74	2.54 (2.35–2.74)*	6.62 (5.62–7.79)*	1.54 (1.29–1.84)*	2.16 (1.74–2.68)*	1.13 (1.01–1.26)**	3.07 (1.33–7.12)**
75–99	4.35 (4.03–4.69)*	13.85 (11.76–16.31)*	2.16 (1.80–2.59)*	3.30 (2.66–4.11)*	1.64 (1.47–1.83)*	7.86 (3.41–18.14)*
Diabetes	1.22 (1.20–1.25)*	1.15 (1.15–1.18)*	1.11 (1.06–1.17)*	1.64 (1.56–1.72)*	1.14 (1.09–1.18)*	1.28 (1.09–1.52)**
Renal disease	2.61 (1.98–3.44)*	1.88 (1.27–2.77)*	3.36 (2.06–5.47)*	3.35 (2.08–5.40)*	3.09 (2.06–4.64)*	2.98 (0.73–12.21)
Cerebrovascular disease	2.09 (1.84–2.37)*	2.14 (1.3–2.50)*	2.25 (1.75–2.89)*	1.61 (1.21–2.15)*	1.98 (1.61–2.43)*	2.71 (1.53–4.79)*
Peripherovascular disease	1.63 (1.55–1.71)*	1.67 (1.58–1.78)*	1.48 (1.32–1.66)*	1.68 (1.51–1.88)*	1.73 (1.59–1.88)*	1.75 (1.31–2.35)*
Cancer	1.37 (1.30–1.45)*	1.17 (1.09–1.26)*	1.71 (1.53–1.92)*	1.48 (1.31–167)*	1.77 (1.62–1.93)*	2.03 (1.51–2.73)*
Obesity	1.36 (1.33–1.39)*	1.22 (1.18–1.26)*	1.49 (1.41–1.57)*	2.19 (2.08–2.31)*	1.48 (1.42–1.53)*	1.44 (1.18–1.75)*
Pulmonary hypertension	4.12 (3.83–4.43)*	4.88 (4.51–5.28)*	3.93 (3.49–4.43)*	3.30 (2.89–3.77)*	3.11 (2.79–3.46)*	3.56 (2.56–4.96)*
Sleep apnea	1.56 (1.51–1.60)*	1.63 (1.57–1.69)*	2.10 (1.97–2.23)*	1.57 (1.47–1.68)*	1.99 (1.90–2.08)*	1.38 (1.09–1.75)**
c-statistic	0.68	0.73	0.69	0.77	0.73	0.80

CI: confidence interval. ^∗𝑃<0.001, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.05.