Treatment with Rhizoma Dioscoreae Extract Has Protective Effect on Osteopenia in Ovariectomized Rats

Table 2

Effect of RDE on BMD and trabecular bone histomorphometric indices after 12 weeks of treatment.

	SHAM	OVX	E2	RDE
BMD (before treatment) (g/cm^2)	0.210±0.064	0.209±0.068	0.207±0.076	0.208±0.061
BMD (after treatment) (g/cm^2)	0.305±0.006	0.181±0.006^b	0.301±0.006^d	0.280±0.009^c
BV/TV (%)	33.46±4.89	12.11±3.77^b	26.45±4.36^d	18.15±3.34^d
ES/BS (%)	3.46±0.88	9.73±1.48^b	4.08±1.63^d	6.15±1.63^d
MS/BS (%)	7.90±1.98	13.54±4.99^b	7.27±2.41^d	10.82±2.53^d
MAR, 𝜇m/d	1.27±0.36	1.87±0.21^b	1.24±0.22^d	1.59±0.25^d
O.Th, 𝜇m	6.16±1.37	7.85±1.79^a	6.44±1.84^c	7.59±1.86

Values are presented as the means ± SD (𝑛=12 in each group).
^a𝑃<0.05 versus SHAM group; ^b𝑃<0.01 versus SHAM group; ^c𝑃<0.05 versus OVX group; ^d𝑃<0.01 versus OVX group.