Treatment with Rhizoma Dioscoreae Extract Has Protective Effect on Osteopenia in Ovariectomized Rats

Table 4

Effect of RDE on trabecular bone microarchitecture after 12 weeks of treatment.

	SHAM	OVX	E2	RDE
BV/TV (%)	23.60±2.03	2.51±0.48^b	14.00±0.83^d	5.09±0.68^c
Tb.Th (𝜇m)	73.44±0.98	51.61±1.87^b	71.32±0.92^d	61.91±0.93^d
Tb.Sp (𝜇m)	181.62±26.48	678.27±33.21^b	319.63±95.91^d	519.29±13.55^c
Tb.N (1/mm)	3.31±0.33	0.48±0.09^b	2.05±0.30^d	0.76±0.05^c
SMI	1.55±0.14	2.10±0.08^a	1.72±0.02	1.89±0.02
DA	1.87±0.18	3.81±0.49^b	2.04±0.05^d	2.64±0.13^d

Values are presented as the means ± SD (𝑛=12 in each group).
^a𝑃<0.05 versus SHAM group; ^b𝑃<0.01 versus SHAM group; ^c𝑃<0.05 versus OVX group; ^d𝑃<0.01 versus OVX group.