Research Article
Facile and Promising Method for Michael Addition of Indole and Pyrrole to Electron-Deficient trans-β-Nitroolefins Catalyzed by a Hydrogen Bond Donor Catalyst Feist’s Acid and Preliminary Study of Antimicrobial Activity
Table 2
Michael addition of indole (4) to nitroolefins 2(a–i) catalyzed by Feist’s acid.
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The reactions were performed on 0.425 mmol scale; bthe isolated yield after column purification; c20 mol% catalyst was used and reactions were run for 72 hours. |