Research Article
Diuretic Activity of the Aqueous Extract Leaves of Ficus glumosa Del. (Moraceae) in Rats
Table 1
Effects of the aqueous extract of F. glumosa on the urinary volume and excretion of Na+, Cl−, and K+.
| Urinary volume and excretion of Na+, Cl−, and K+ | Drugs (mg/kg) | Urinary volume | Na+ excretion | Cl− excretion | K+ excretion |
(mL/kg/24 h) | (mEq/kg/24 h) | (mEq/kg/24 h) | (mEq/kg/24 h) |
| Control | 249.31 ± 4.93 | 18.27 ± 1.01 | 15.12 ± 2.11 | 19.54 ± 0.85 | Extract | | | | | 225 | 292.15 ± 4.69*** | 53.92 ± 2.12*** | 50.87 ± 2.16*** | 37.58 ± 1.51*** | 300 | 322.34 ± 4.14*** | 104.24 ± 1.26*** | 101.27 ± 1.03*** | 54.29 ± 0.72*** | 375 | 393.04 ± 4.03*** | 153.78 ± 1.92*** | 150.89 ± 1.42*** | 46.21 ± 2.38*** | Furosemide (2 mg/kg) | 448.17 ± 2.86*** | 95.45 ± 6.45*** | 92.54 ± 6.22*** | 35.99 ± 2.63*** | Amiloride H. (14 mg/kg) | 278.07 ± 6.41** | 75.30 ± 2.36*** | 72.34 ± 2.44*** | 25.51 ± 0.88** |
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Values are means ± SEM, , , , significant difference compared to the control.
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