Research Article

Diuretic Activity of the Aqueous Extract Leaves of Ficus glumosa Del. (Moraceae) in Rats

Table 4

Effects of the aqueous extract of F. glumosa on the serum parameters.

Drugs (mg/kg)Glucose (mg/dl)Creatinine (mg/dl)Urea (mg/dl)Albumin (g/l)Aldosterone (pg/mL) Na+ (méq·L−1) K+ (méq·L−1)POSM (mosmol/kg)

Control94.39 ± 10.450.62 ± 0.4123.27 ± 4.2542.8 ± 5.01293.4 ± 36.231.73 ± 0.551.85 ± 0.85262 ± 21
 Extract
  225 97.39 ± 10.45*0.69 ± 0.73*24.49 ± 2.1843.4 ± 4.11295.3 ± 28.557.79 ± 1.79***3.99 ± 2.82***269 ± 22**
  300 96.27 ± 11.22*0.72 ± 0.46**24.55 ± 4.77*44.6 ± 5.03**297.4 ± 29.34**9.68 ± 1.53***4.89 ± 3.65***270 ± 31***
  375 98.28 ± 7.10*0.89 ± 0.20***25.89 ± 5.26***44.8 ± 6.06***304.25 ± 94.81***10.54 ± 1.92***5.62 ± 3.78***275 ± 42***
Furosemide (2 mg/kg)98.13 ± 6.23*0.78 ± 0.22***24.89 ± 4.29*44.4 ± 5.13**303.11 ± 76.77***11.14 ± 1.12***6.34 ± 2.11***276 ± 32***
Amiloride H. (14 mg/kg)97.14 ± 7.21*0.76 ± 0.16***26.77 ± 3.95***43.7 ± 4.36***294.45 ± 69.54***7.54 ± 1.33***8.66 ± 3.69***275 ± 44***

Values are means ± SEM, , , , and , significant difference compared to the control. POSM: plasma osmolality.