Research Article
Diuretic Activity of the Aqueous Extract Leaves of Ficus glumosa Del. (Moraceae) in Rats
Table 4
Effects of the aqueous extract of F. glumosa on the serum parameters.
| Drugs (mg/kg) | Glucose (mg/dl) | Creatinine (mg/dl) | Urea (mg/dl) | Albumin (g/l) | Aldosterone (pg/mL) | Na+ (méq·L−1)
| K+ (méq·L−1) | POSM (mosmol/kg) |
| Control | 94.39 ± 10.45 | 0.62 ± 0.41 | 23.27 ± 4.25 | 42.8 ± 5.01 | 293.4 ± 36.23 | 1.73 ± 0.55 | 1.85 ± 0.85 | 262 ± 21 | Extract | | | | | | | | | 225 | 97.39 ± 10.45* | 0.69 ± 0.73* | 24.49 ± 2.18 | 43.4 ± 4.11 | 295.3 ± 28.55 | 7.79 ± 1.79*** | 3.99 ± 2.82*** | 269 ± 22** | 300 | 96.27 ± 11.22* | 0.72 ± 0.46** | 24.55 ± 4.77* | 44.6 ± 5.03** | 297.4 ± 29.34** | 9.68 ± 1.53*** | 4.89 ± 3.65*** | 270 ± 31*** | 375 | 98.28 ± 7.10* | 0.89 ± 0.20*** | 25.89 ± 5.26*** | 44.8 ± 6.06*** | 304.25 ± 94.81*** | 10.54 ± 1.92*** | 5.62 ± 3.78*** | 275 ± 42*** | Furosemide (2 mg/kg) | 98.13 ± 6.23* | 0.78 ± 0.22*** | 24.89 ± 4.29* | 44.4 ± 5.13** | 303.11 ± 76.77*** | 11.14 ± 1.12*** | 6.34 ± 2.11*** | 276 ± 32*** | Amiloride H. (14 mg/kg) | 97.14 ± 7.21* | 0.76 ± 0.16*** | 26.77 ± 3.95*** | 43.7 ± 4.36*** | 294.45 ± 69.54*** | 7.54 ± 1.33*** | 8.66 ± 3.69*** | 275 ± 44*** |
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Values are means ± SEM, , , , and , significant difference compared to the control. POSM: plasma osmolality.
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