Research Article

Changes in Iron Metabolism and Oxidative Status in STZ-Induced Diabetic Rats Treated with Bis(maltolato) Oxovanadium (IV) as an Antidiabetic Agent

Table 3

Activity of superoxide dismutase (SOD), catalase (CAT), NAD(P)H: quinone-oxidoreductase-1 (NQO1), and protein carbonyl group levels in the liver on day 35.

CDMDMVDMVH

SOD (U/mg protein)685 ± 81672 ± 83743 ± 74718 ± 70NS
CAT (U/mg protein)389 ± 97295 ± 29a402 ± 76b733 ± 73a,b,cP < 0.001
NQO1 (mU/mg protein)173 ± 72269 ± 87a242 ± 59155 ± 57b,cP < 0.05
Protein carbonyl groups (pm/mg protein) 134 ± 33130 ± 38196 ± 40a,b 186 ± 21a,bP < 0.01

Values shown are means ± SD. C: control rats; DM: diabetic STZ rats; DMV: diabetic STZ rats treated with 1 mgV/day; DMVH: diabetic STZ rats treated with 3 mgV/day. aDifferent from group C; bdifferent from group DM; cdifferent from group DMV. P < 0.05. NS: not significant.