Frequency of CFTR, SPINK1, and Cathepsin B Gene Mutation in North Indian Population: Connections between Genetics and Clinical Data

Table 2

Demographic and clinical profiles of 150 chronic pancreatitis cases (carriers versus noncarriers) screened for SPINK1 gene.

Characteristics	Carriers (88)	Noncarriers (62)	P value
Age in months (M ± SD)	33.9±11.7	32.3±11.6	0.395
Weight in kg (M ± SD)	56.0±13.3	52.2±12.8	0.082
BMI (M ± SD)	21.2±4.6	20.1±4.5	0.132
FBS (M ± SD)	56.2±102.6	48.2±103.8	0.567
PPBS (M ± SD)	153.6±79.3	168.9±68.5	0.210
HbA1C (M ± SD)	5.93±1.7	5.23±1.5	0.225
Triglyceride (M ± SD)	118.2±92.0	116.3±59.56	0.883
Total cholesterol	156.1±51.29	162±49.3	0.381
HDL-cholesterol	35.8±8.82	76.3±9.86	0.002*
LDL-cholesterol	86.2±32.2	88.8±28.7	0.432
VLDL-cholesterol	26.9±12.41	17.5±7.77	0.012*
Serum amylase	1023±488.8	727.7±480	0.013*
Serum lipase	732.40±452.2	888.9±420	0.112
Serum calcium	8.9±1.2	9.11±1.09	0.226

∗Mean ± SD (*significant association found).