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| Platelet aggregometry |
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| Photo-optical platelet aggregometry [79] | Platelet-rich plasma is taken to check the platelet aggregation. |
| Impedance platelet aggregometry [80] | Platelet aggregation is checked by using the whole blood by electrical impedance. |
| Light-scattering platelet aggregometry [81] | It is a combination of laser light scattering and aggregometry to monitor platelet microaggregate formation. |
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| Point-of-care for platelet function tests |
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| Ultegra rapid platelet function assay (RPFA) [82] | RPFA is a simple and fast, automated point-of-care device that monitors GPIIb-IIIa inhibition. This test is based on platelet agglutination from interaction between unblocked GPIIb-IIIa receptors and fibrinogen-coated beads. |
| Platelet-activating clotting test (PACT) assay [83] | The PACT assay, HemoSTATUS, measures ACT without a platelet activator, comparing it with ACTs obtained with increasing concentrations of platelet-activating factor (PAF). |
| Platelet function analyzer (PFA-100) [84] | PFA-100 exposes platelets within citrated whole blood to high shear stress through a capillary tube, followed by an aperture in a membrane coated with collagen and either ADP or epinephrine. The platelets adhere and aggregate until the aperture is occluded, and the time to this closure is recorded. |
| Plateletworks test [85] | The Plateletworks is a point-of-care test that uses a Coulter counter to measure platelet-count ratio, red blood cell count, hemoglobin, and hematocrit. Platelet count is measured in a control sample in which aggregation is prevented by EDTA and compared with the platelet count in an agonist-stimulated (ADP or collagen) sample. |
| Clot signature analyzer [86] | This test uses nonanticoagulated whole blood and can measure several aspects of platelet function and clotting properties. |
| Thromboelastography [87] | This device measures clot strength and gives a global assessment of hemostasis. |
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