HPV Infection in Esophageal Squamous Cell Carcinoma and Its Relationship to the Prognosis of Patients in Northern China

Figure 2

Kaplan-Meier estimates of survival among the study patients, according to tumor HPV status or p16-expression status. For 5-year overall survival rate (a) and 5-year progression-free survival rate (b), HPV was significantly associated with improved outcomes (𝑃=0.002, 𝑃=0.001, resp.). For 5-year OS rate (c) and 5-year progression-free survival rate (d), p16 was significantly associated with improved outcomes (𝑃=0.021, 𝑃=0.007, resp.).

(a) Overall survival according to tumor HPV status

(b) Progression-free survival according to tumor HPV status

(c) Overall survival according to p16 expression

(d) Progression-free survival according to p16 expression