The Connection between the Toxicity of Anthracyclines and Their Ability to Modulate the P-Glycoprotein-Mediated Transport in A549, HepG2, and MCF-7 Cells
Figure 1
Representative dose-response curves following exposure to DOX and ACL of A549, HepG2, and MCF-7 cells. The evaluation of cell survival was assessed by MTT assay. *, the effect of DOX and ACL on the viability of solid tumor cells. +, changes between the probes preincubated with Verapamil. The values are the mean ± SD of four independent experiments.
