The Connection between the Toxicity of Anthracyclines and Their Ability to Modulate the P-Glycoprotein-Mediated Transport in A549, HepG2, and MCF-7 Cells
Figure 2
The effect of Verapamil on ACL and DOX accumulation in tested cells. The accumulation of ACL and DOX in A549, HepG2, and MCF-7 cell lines was examined after 2 h incubation with IC50 of the drugs and 24 h after incubation without drugs. The excitation and emission wavelengths were for ACL nm and nm and DOX nm and , respectively. *Values are statistically significant in comparison to the control, untreated cells, . +Values are statistically significant in comparison to the cells incubated without Verapamil, .
