The Scientific World Journal / 2014 / Article / Tab 1 / Review Article
Food Antimicrobials Nanocarriers Table 1 Advantages and disadvantages of nanoencapsulated systems of food antimicrobials.
Delivery system Physical morphology Advantage Disadvantage Reference Nanoemulsions Liquid Transparent/translucent systems suitable to use in beverages Carrier of hydrophobic compounds Rapid absorption Toxicological safe Good shelf stability Rapid release Low stability in acidic condition Low-energy methods are limited in food sector [13 ] [59 ] Nanoparticles (a) Nanospheres Solid Large surface-to-volume ratios Controlled release of insoluble actives Lack of stability of some actives High production costs [60 ] [61 ] (b) Nanocapsules Solid The use of natural polymers such as polysaccharide and proteins can increase bioavailability and biodegradability Large dispersion of encapsulated actives A purification process is necessary after the synthesis of nanocapsules [60 ] [61 ] [62 ] [63 ] (c) Solid lipid nanoparticles Solid Increase the aqueous solubility of the compound Produce a prolonged release and decrease the toxic side effects of the compound Rapid formulation development Recrystallization risk and low encapsulation load [13 ] [64 ] Liposomes Liquid Capability to either encapsulate water-soluble drugs in their cavity or to solubilize lipophilic drugs in their bilayer Targetability High stability of compounds in foodstuff with high water content Large-scale production Rapid release Short shelf lives [65 ] [66 ] [67 ] Nanofibers Solid Large surface area and porosity Possibility of large-scale production Capability to carry heat sensitive compounds High gas permeability Biopolymers solubility limits their use in electrospinning [68 ] [69 ] [70 ]