Nanospray Drying as a Novel Technique for the Manufacturing of Inhalable NSAID Powders

Table 2

Aerodynamic properties of nanospray-dried Klys/leu (15% leu, 30% IPA) powders after ACI experiments: emitted dose (ED), mass median aerodynamic diameter (MMAD), fine particles fraction (FPF), and fine particle dose (FPD).

Batch	Feed concentration (%), nozzle (), and temperature ()	Emitted dose (%)	MMAD (µm)	FPF (%)	FPD (mg)
#1	5%	99.2 ± 0.1	5.69 ± 0.23	21.9 ± 2.5	6.27 ± 0.5
#2	3%	99.2 ± 0.1	5.44 ± 0.55	29.5 ± 2.3	8.16 ± 0.24
#3	5%	99.1 ± 0.1	4.25 ± 0.12	50.4 ± 1.9	12.7 ± 1.1
#5	5%	100.0 ± 0.1	3.72 ± 0.07	66.3 ± 1.0	16.9 ± 0.6
#6	3%	96.7 ± 4.2	6.25 ± 0.11	31.6 ± 1.6	7.85 ± 1.2
#9	5%	97.3 ± 1.0	4.58 ± 0.14	45.6 ± 2.2	12.2 ± 1.3