Nonlinear Quantitative Radiation Sensitivity Prediction Model Based on NCI-60 Cancer Cell Lines

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left">Gene symbol</td><td align="center">Gene description</td><td align="center">Location</td><td align="left">Sequence</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left"><i>CD44 </i></td><td align="center">CD44 molecule (Indian blood group)</td><td align="center">11p13</td><td align="left">Chromosome: 11; NC_000011.10 (35138870…35232402)</td></tr><tr><td align="left"><i>ANXA2 </i></td><td align="center">Annexin A2</td><td align="center">15q22.2</td><td align="left">Chromosome: 15; NC_000015.10 (60347151…60397986, complement)</td></tr><tr><td align="left"><i>VEGFC </i></td><td align="center">Vascular endothelial growth factor C</td><td align="center">4q34.3</td><td align="left">Chromosome: 4; NC_000004.12 (176683538…176792745, complement)</td></tr><tr><td align="left"><i>CTGF </i></td><td align="center">Connective tissue growth factor</td><td align="center">6q23.1</td><td align="left">Chromosome: 6; NC_000006.12 (131948176…131951378, complement)</td></tr><tr><td align="left"><i>PTK2 </i></td><td align="center">PTK2 protein tyrosine kinase 2</td><td align="center">8q24.3</td><td align="left">Chromosome: 8; NC_000008.11 (140658382…141001313, complement)</td></tr><tr><td align="left"><i>TJP1 </i></td><td align="center">Tight junction protein 1 (zona occludens 1)</td><td align="center">15q13</td><td align="left">Chromosome: 15; NC_000015.10 (29700134…29968835, complement)</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Six hub genes identified by gene regulatory network analysis.

The Scientific World Journal

tab2

Table 2

Table 2: Nonlinear Quantitative Radiation Sensitivity Prediction Model Based on NCI-60 Cancer Cell Lines 